{"id":9136,"date":"2023-07-21T09:49:11","date_gmt":"2023-07-21T09:49:11","guid":{"rendered":"https:\/\/vospan.com\/?p=9136"},"modified":"2024-03-20T08:18:13","modified_gmt":"2024-03-20T08:18:13","slug":"hoa-mo-mien-dich-ihc-ky-thuat-nhuom-dot-pha-trong-chuan-doan-mo-benh-hoc","status":"publish","type":"post","link":"https:\/\/vospan.com\/hoa-mo-mien-dich-ihc-ky-thuat-nhuom-dot-pha-trong-chuan-doan-mo-benh-hoc\/","title":{"rendered":"H\u00f3a m\u00f4 mi\u1ec5n d\u1ecbch (IHC): K\u1ef9 thu\u1eadt nhu\u1ed9m \u0111\u1ed9t ph\u00e1 trong chu\u1ea9n \u0111o\u00e1n m\u00f4 b\u1ec7nh h\u1ecdc"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_68_1 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<label class=\"ez-toc-title ez-toc-toggle\" style=\"cursor: pointer\">T&oacute;m t\u1eaft n\u1ed9i dung<\/label>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #0a0a0a;color:#0a0a0a\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #0a0a0a;color:#0a0a0a\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/vospan.com\/hoa-mo-mien-dich-ihc-ky-thuat-nhuom-dot-pha-trong-chuan-doan-mo-benh-hoc\/#Su_lien_ket_IHC\" title=\"S\u1ef1 li\u00ean k\u1ebft IHC\u00a0\">S\u1ef1 li\u00ean k\u1ebft IHC\u00a0<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/vospan.com\/hoa-mo-mien-dich-ihc-ky-thuat-nhuom-dot-pha-trong-chuan-doan-mo-benh-hoc\/#Khang_the_la_gi\" title=\"Kh\u00e1ng th\u1ec3 l\u00e0 g\u00ec?\">Kh\u00e1ng th\u1ec3 l\u00e0 g\u00ec?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/vospan.com\/hoa-mo-mien-dich-ihc-ky-thuat-nhuom-dot-pha-trong-chuan-doan-mo-benh-hoc\/#Tao_khang_the\" title=\"T\u1ea1o kh\u00e1ng th\u1ec3\">T\u1ea1o kh\u00e1ng th\u1ec3<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/vospan.com\/hoa-mo-mien-dich-ihc-ky-thuat-nhuom-dot-pha-trong-chuan-doan-mo-benh-hoc\/#Hoa_mo_mien_dich_va_cac_ung_dung_trong_tuong_lai\" title=\"H\u00f3a m\u00f4 mi\u1ec5n d\u1ecbch v\u00e0 c\u00e1c \u1ee9ng d\u1ee5ng trong t\u01b0\u01a1ng lai\">H\u00f3a m\u00f4 mi\u1ec5n d\u1ecbch v\u00e0 c\u00e1c \u1ee9ng d\u1ee5ng trong t\u01b0\u01a1ng lai<\/a><\/li><\/ul><\/nav><\/div>\n<div class=\"MjjYud\">\n<div class=\"g Ww4FFb vt6azd tF2Cxc asEBEc\" lang=\"vi\" data-hveid=\"CBUQAA\" data-ved=\"2ahUKEwi5lKOkwJ-AAxUY0GEKHYovDQwQFSgAegQIFRAA\">\n<div class=\"GLI8Bc UK95Uc\" data-snc=\"ih6Jnb_OlxCRe\">\n<div class=\"Z26q7c UK95Uc VGXe8\" data-sncf=\"2\" data-snf=\"nke7rc\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"MjjYud\">\n<div class=\"g Ww4FFb vt6azd tF2Cxc asEBEc\" lang=\"vi\" data-hveid=\"CBQQAA\" data-ved=\"2ahUKEwi5lKOkwJ-AAxUY0GEKHYovDQwQFSgAegQIFBAA\">\n<div class=\"GLI8Bc UK95Uc\" data-snc=\"ih6Jnb_t4mqOd\">\n<p class=\"Z26q7c UK95Uc jGGQ5e VGXe8\" data-snf=\"x5WNvb\" data-snhf=\"0\">Hi\u1ec7n nay, <a href=\"https:\/\/vospan.com\/product-category\/thiet-bi-y-te\/giai-phau-benh\/nhuom-dac-biet-ihc-ish\/\">ho\u00e1 m\u00f4 mi\u1ec5n d\u1ecbch<\/a> \u0111\u00e3 tr\u1edf th\u00e0nh m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p ph\u1ed5 bi\u1ebfn, l\u00fd t\u01b0\u1edfng cho c\u00e1c nh\u00e0 gi\u1ea3i ph\u1eabu b\u1ec7nh trong vi\u1ec7c chu\u1ea9n \u0111o\u00e1n b\u1ec7nh.<\/p>\n<p class=\"Z26q7c UK95Uc jGGQ5e VGXe8\" data-snf=\"x5WNvb\" data-snhf=\"0\"><strong style=\"font-size: 23.04px;\"><a href=\"https:\/\/vospan.com\/product-category\/thiet-bi-y-te\/giai-phau-benh\/nhuom-dac-biet-ihc-ish\/\">IHC<\/a> l\u00e0 g\u00ec?<\/strong><\/p>\n<\/div>\n<\/div>\n<\/div>\n<p class=\"section-header no-padding-top\" data-gtm-vis-recent-on-screen-452244_570=\"577\" data-gtm-vis-first-on-screen-452244_570=\"577\" data-gtm-vis-total-visible-time-452244_570=\"100\" data-gtm-vis-has-fired-452244_570=\"1\">C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u s\u1eed d\u1ee5ng ph\u01b0\u01a1ng ph\u00e1p nhu\u1ed9m m\u00f4 b\u1ec7nh h\u1ecdc \u0111\u1ec3 kh\u00e1m ph\u00e1 nh\u1eefng ph\u00e1t hi\u1ec7n m\u1edbi trong m\u1ed9t m\u1eabu m\u00f4. \u0110i\u1ec1u n\u00e0y cho ph\u00e9p h\u1ecd x\u00e2y d\u1ef1ng m\u1ed9t l\u00fd thuy\u1ebft v\u1ec1 nguy\u00ean nh\u00e2n d\u1eabn \u0111\u1ebfn b\u1ec7nh t\u1eadt, v\u00e0 sau \u0111\u00f3 n\u00f3 h\u01b0\u1edbng c\u00e1c b\u01b0\u1edbc ti\u1ebfp theo trong nghi\u00ean c\u1ee9u chuy\u1ec3n h\u00f3a.<\/p>\n<p data-gtm-vis-recent-on-screen-452244_570=\"577\" data-gtm-vis-first-on-screen-452244_570=\"577\" data-gtm-vis-total-visible-time-452244_570=\"100\" data-gtm-vis-has-fired-452244_570=\"1\">Ph\u00e1t hi\u1ec7n \u0111\u1ea7u ti\u00ean t\u1eeb m\u1ed9t v\u1ebft th\u01b0\u1eddng quy ho\u1eb7c v\u1ebft s\u01a1 c\u1ea5p s\u1eed d\u1ee5ng hai m\u00e0u t\u01b0\u01a1ng ph\u1ea3n, t\u00edm xanh (nh\u00e2n t\u1ebf b\u00e0o nhu\u1ed9m hematoxylin) v\u00e0 h\u1ed3ng (t\u1ebf b\u00e0o ch\u1ea5t nhu\u1ed9m eosin), x\u00e1c \u0111\u1ecbnh c\u1ea5u tr\u00fac v\u00e0 thay \u0111\u1ed5i ki\u1ec3u m\u1eabu trong m\u00f4 (<em>H\u00ecnh 1a<\/em>). V\u1ebft n\u00e0y \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 v\u1ebft Hematoxylin &amp; Eosin ho\u1eb7c H&amp;E.\u00a0Ph\u00e1t hi\u1ec7n ban \u0111\u1ea7u v\u1edbi vi\u1ec7c nhu\u1ed9m ti\u00eau b\u1ea3n H&amp;E, m\u00e0u h\u1ed3ng v\u00e0 xanh lam x\u00e1c \u0111\u1ecbnh xem c\u00f3 c\u1ea7n th\u00eam th\u00f4ng tin \u0111\u1ec3 l\u00e0m r\u00f5 k\u1ebft qu\u1ea3 hay kh\u00f4ng.<\/p>\n<figure id=\"attachment_9139\" aria-describedby=\"caption-attachment-9139\" style=\"width: 602px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-9139\" src=\"https:\/\/vospan.com\/wp-content\/uploads\/2023\/07\/Anh-man-hinh-2023-07-21-luc-15.46.18-300x107.png\" alt=\"H\u00f3a m\u00f4 mi\u1ec5n d\u1ecbch (IHC)\" width=\"602\" height=\"215\" srcset=\"https:\/\/vospan.com\/wp-content\/uploads\/2023\/07\/Anh-man-hinh-2023-07-21-luc-15.46.18-300x107.png 300w, https:\/\/vospan.com\/wp-content\/uploads\/2023\/07\/Anh-man-hinh-2023-07-21-luc-15.46.18-1024x364.png 1024w, https:\/\/vospan.com\/wp-content\/uploads\/2023\/07\/Anh-man-hinh-2023-07-21-luc-15.46.18-768x273.png 768w, https:\/\/vospan.com\/wp-content\/uploads\/2023\/07\/Anh-man-hinh-2023-07-21-luc-15.46.18-1536x546.png 1536w, https:\/\/vospan.com\/wp-content\/uploads\/2023\/07\/Anh-man-hinh-2023-07-21-luc-15.46.18-510x181.png 510w, https:\/\/vospan.com\/wp-content\/uploads\/2023\/07\/Anh-man-hinh-2023-07-21-luc-15.46.18.png 1654w\" sizes=\"(max-width: 602px) 100vw, 602px\" \/><figcaption id=\"caption-attachment-9139\" class=\"wp-caption-text\">H\u00ecnh 1. Ung th\u01b0 bi\u1ec3u m\u00f4 tuy\u1ebfn ru\u1ed9t s\u1eed d\u1ee5ng thu\u1ed1c nhu\u1ed9m H&amp;E v\u00e0 IHC<\/figcaption><\/figure>\n<h2 class=\"text-title\"><span class=\"ez-toc-section\" id=\"Su_lien_ket_IHC\"><\/span><strong>S\u1ef1 li\u00ean k\u1ebft <a href=\"https:\/\/vospan.com\/product-category\/thiet-bi-y-te\/giai-phau-benh\/nhuom-dac-biet-ihc-ish\/\">IHC\u00a0<\/a><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>H\u00f3a m\u00f4 mi\u1ec5n d\u1ecbch (<a href=\"https:\/\/vospan.com\/product-category\/thiet-bi-y-te\/giai-phau-benh\/nhuom-dac-biet-ihc-ish\/\">IHC<\/a>) l\u00e0 m\u1ed9t k\u1ef9 thu\u1eadt nhu\u1ed9m m\u00e0u th\u1ee9 c\u1ea5p chuy\u00ean bi\u1ec7t, s\u1eed d\u1ee5ng ch\u1ea5t nhi\u1ec5m s\u1eafc ho\u1eb7c ch\u1ea5t k\u1ebft t\u1ee7a c\u00f3 m\u00e0u, \u0111\u1ec3 l\u00e0m \u0111\u1ea7u m\u1ed1i cho c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u quan s\u00e1t v\u1ec1 nh\u1eefng b\u1ea5t th\u01b0\u1eddng. <a href=\"https:\/\/vospan.com\/product-category\/thiet-bi-y-te\/giai-phau-benh\/nhuom-dac-biet-ihc-ish\/\">IHC<\/a> c\u0169ng s\u1eed d\u1ee5ng hematoxylin l\u00e0m ch\u1ea5t ph\u1ea3n m\u00e0u \u0111\u1ec3 nhu\u1ed9m ph\u1ea7n m\u00f4.\u00a0Hematoxylin \u0111\u00f3ng vai tr\u00f2 t\u01b0\u01a1ng ph\u1ea3n v\u1edbi ch\u1ea5t nhi\u1ec5m s\u1eafc v\u00e0 n\u00f3 c\u0169ng \u0111\u1ecbnh v\u1ecb v\u00e0o nh\u00e2n \u0111\u1ec3 nhu\u1ed9m ch\u1ea5t nhi\u1ec5m s\u1eafc (<em>H\u00ecnh 1b &amp; 1c<\/em>).\u00a0<a href=\"https:\/\/vospan.com\/product-category\/thiet-bi-y-te\/giai-phau-benh\/nhuom-dac-biet-ihc-ish\/\">IHC<\/a> l\u00e0 m\u1ed9t x\u00e9t nghi\u1ec7m ti\u00eau chu\u1ea9n trong ph\u00f2ng th\u00ed nghi\u1ec7m \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n nh\u1edd ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch sinh h\u1ecdc \u1edf \u0111\u1ed9ng v\u1eadt c\u00f3 v\u00fa.\u00a0M\u1ed9t t\u1eadp h\u1ee3p con c\u1ee7a c\u00e1c t\u1ebf b\u00e0o m\u00e1u c\u1ee7a \u0111\u1ed9ng v\u1eadt c\u00f3 v\u00fa \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 t\u1ebf b\u00e0o lympho c\u00f3 th\u1ec3 ph\u00e1t hi\u1ec7n ch\u1ea5t trong c\u01a1 th\u1ec3. C\u00e1c t\u1ebf b\u00e0o ch\u1ee7 th\u1ec3 hi\u1ec7n c\u00e1c c\u1ea5u tr\u00fac b\u00e1o hi\u1ec7u cho c\u00e1c t\u1ebf b\u00e0o lympho r\u1eb1ng c\u00e1c t\u1ebf b\u00e0o n\u00e0y thu\u1ed9c v\u1ec1 ch\u00ednh n\u00f3 ng\u0103n ch\u1eb7n ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch ph\u00e1 h\u1ee7y ch\u00fang.<\/p>\n<figure style=\"width: 415px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.leicabiosystems.com\/sites\/default\/files\/media_image-file\/2022-09\/B-cell-Lymphocyte_0.jpg\" alt=\"\" width=\"415\" height=\"429\" \/><figcaption class=\"wp-caption-text\">H\u00ecnh 2. T\u1ebf b\u00e0o Lympho B<\/figcaption><\/figure>\n<p>C\u00e1c t\u1ebf b\u00e0o lympho t\u1ebf b\u00e0o B (<em>H\u00ecnh 2<\/em>) s\u1ea3n xu\u1ea5t c\u00e1c protein chuy\u00ean bi\u1ec7t \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 kh\u00e1ng th\u1ec3 li\u00ean k\u1ebft v\u1edbi ch\u1ea5t kh\u00f4ng t\u1ef1 th\u00e2n, \u0111\u00e1nh d\u1ea5u n\u00f3 \u0111\u1ec3 c\u00e1c t\u1ebf b\u00e0o lympho kh\u00e1c ph\u00e1 h\u1ee7y. <a href=\"https:\/\/vospan.com\/product-category\/thiet-bi-y-te\/giai-phau-benh\/nhuom-dac-biet-ihc-ish\/\">IHC<\/a> cung c\u1ea5p m\u1ed9t c\u00e1i nh\u00ecn chung v\u00e0o m\u00f4 \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh xem c\u00f3 bi\u1ec3u hi\u1ec7n protein hay kh\u00f4ng b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng kh\u00e1ng th\u1ec3.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Khang_the_la_gi\"><\/span><strong>Kh\u00e1ng th\u1ec3 l\u00e0 g\u00ec?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Kh\u00e1ng th\u1ec3 l\u00e0 c\u00e1c protein chuy\u00ean bi\u1ec7t \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 globulin mi\u1ec5n d\u1ecbch \u0111\u01b0\u1ee3c t\u1ea1o ra b\u1edfi c\u00e1c t\u1ebf b\u00e0o B \u0111\u1ec3 ph\u1ea3n \u1ee9ng l\u1ea1i v\u1edbi kh\u00e1ng nguy\u00ean. Kh\u00e1ng nguy\u00ean l\u00e0 nh\u1eefng v\u1eadt ch\u1ea5t l\u1ea1 g\u00e2y ra ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch ho\u1eb7c s\u1ea3n xu\u1ea5t kh\u00e1ng th\u1ec3. Ch\u00fang l\u00e0 c\u00e1c protein globulin mi\u1ec5n d\u1ecbch h\u00ecnh ch\u1eef Y li\u00ean k\u1ebft v\u1edbi c\u00e1c kh\u00e1ng nguy\u00ean (<em>H\u00ecnh 3<\/em>).\u00a0Khu v\u1ef1c \u1edf cu\u1ed1i m\u1ed7i Y-arm nh\u1eadn bi\u1ebft v\u00e0 li\u00ean k\u1ebft c\u1ee5 th\u1ec3 v\u1edbi kh\u00e1ng nguy\u00ean ho\u1eb7c m\u1ee5c ti\u00eau. C\u00e1c khu v\u1ef1c li\u00ean k\u1ebft kh\u00e1ng th\u1ec3-kh\u00e1ng nguy\u00ean n\u00e0y kh\u1edbp v\u1edbi nhau m\u1ed9t c\u00e1ch ch\u00ednh x\u00e1c, ng\u0103n v\u1eadt ch\u1ea5t l\u1ea1 v\u00e0o kh\u00e1ng th\u1ec3. Kh\u00e1ng nguy\u00ean, ho\u1eb7c v\u1eadt ch\u1ea5t l\u1ea1, \u0111\u01b0\u1ee3c \u0111\u00e1nh d\u1ea5u \u0111\u1ec3 lo\u1ea1i b\u1ecf b\u1edfi c\u00e1c t\u1ebf b\u00e0o chuy\u00ean bi\u1ec7t kh\u00e1c. \u0110\u00e2y l\u00e0 c\u01a1 ch\u1ebf b\u1ea3o v\u1ec7 t\u1ef1 nhi\u00ean c\u1ee7a c\u01a1 th\u1ec3.\u00a0<a href=\"https:\/\/vospan.com\/product-category\/thiet-bi-y-te\/giai-phau-benh\/nhuom-dac-biet-ihc-ish\/\">IHC<\/a> m\u00f4 h\u00ecnh h\u00f3a c\u01a1 ch\u1ebf n\u00e0y b\u00ean ngo\u00e0i c\u01a1 th\u1ec3 tr\u00ean m\u1ed9t ph\u1ea7n m\u00f4 m\u00f4 ph\u1ecfng h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch c\u1ee7a c\u01a1 th\u1ec3 \u0111\u1ec3 t\u00ecm (Kh\u00e1ng th\u1ec3) v\u00e0 \u0111\u00e1nh d\u1ea5u c\u00e1c m\u1ee5c ti\u00eau (Kh\u00e1ng nguy\u00ean).<\/p>\n<figure style=\"width: 591px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.leicabiosystems.com\/sites\/default\/files\/media_image-file\/2022-09\/Antibody-binding.jpg\" alt=\"\" width=\"591\" height=\"174\" \/><figcaption class=\"wp-caption-text\">H\u00ecnh 3. Li\u00ean k\u1ebft kh\u00e1ng th\u1ec3<\/figcaption><\/figure>\n<div class=\"col-12 field__item\">\n<div class=\"text text--simple paragraph paragraph--type--simple-text-element paragraph--view-mode--default\">\n<h2 class=\"text-title\"><span class=\"ez-toc-section\" id=\"Tao_khang_the\"><\/span><strong>T\u1ea1o kh\u00e1ng th\u1ec3<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<div>\n<p>T\u1ea1o ra c\u00e1c kh\u00e1ng th\u1ec3 m\u1ea1nh, ch\u1ea5t l\u01b0\u1ee3ng cao cho nghi\u00ean c\u1ee9u v\u00e0 kh\u00e1m ph\u00e1 l\u00e0 m\u1ed9t qu\u00e1 tr\u00ecnh r\u1ea5t nghi\u00eam ng\u1eb7t.<\/p>\n<p>C\u00e1c protein li\u00ean quan x\u00e1c \u0111\u1ecbnh m\u1ed9t lo\u1ea1i kh\u1ed1i u c\u1ee5 th\u1ec3 \u0111\u01b0\u1ee3c ph\u00e2n l\u1eadp v\u00e0 nh\u1eefng m\u1ea3nh protein nh\u1ecf n\u00e0y \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 c\u1ea5y v\u00e0o \u0111\u1ed9ng v\u1eadt th\u00ed nghi\u1ec7m chuy\u00ean bi\u1ec7t nh\u1eb1m k\u00edch ho\u1ea1t ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch c\u1ee7a ch\u00fang.\u00a0H\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch c\u1ee7a \u0111\u1ed9ng v\u1eadt s\u1ebd t\u1ea1o ra ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch, t\u1ea1o ra kh\u00e1ng th\u1ec3.\u00a0Sau khi c\u00f3 \u0111\u1ee7 m\u1ee9c \u0111\u1ed9 c\u00e1c kh\u00e1ng th\u1ec3 n\u00e0y \u0111\u01b0\u1ee3c t\u1ea1o ra, c\u00e1c t\u1ebf b\u00e0o l\u00e1ch c\u1ee7a \u0111\u1ed9ng v\u1eadt s\u1ebd \u0111\u01b0\u1ee3c thu ho\u1ea1ch v\u00e0 c\u00e1c t\u1ebf b\u00e0o B \u0111\u01b0\u1ee3c ph\u00e2n l\u1eadp.\u00a0C\u00e1c t\u1ebf b\u00e0o \u0111\u01b0\u1ee3c gi\u1eef l\u1ea1i nh\u01b0ng kh\u00f4ng th\u1ec3 ph\u00e1t tri\u1ec3n trong m\u00f4i tr\u01b0\u1eddng nu\u00f4i c\u1ea5y.<\/p>\n<p>\u0110\u1ec3 ph\u00e1t tri\u1ec3n ho\u1eb7c t\u0103ng sinh trong m\u00f4i tr\u01b0\u1eddng nu\u00f4i c\u1ea5y, c\u00e1c t\u1ebf b\u00e0o B l\u00e1ch ph\u1ea3i \u0111\u01b0\u1ee3c \u0111\u01b0a v\u00e0o m\u1ed9t t\u1ebf b\u00e0o u t\u1ee7y \u00e1c t\u00ednh chuy\u00ean bi\u1ec7t.\u00a0\u0110\u1eb7c t\u00ednh \u00e1c t\u00ednh c\u1ee7a d\u00f2ng t\u1ebf b\u00e0o u t\u1ee7y khi\u1ebfn n\u00f3 tr\u1edf n\u00ean b\u1ea5t t\u1eed, nh\u01b0ng n\u00f3 kh\u00f4ng c\u00f3 kh\u1ea3 n\u0103ng t\u1ea1o ra kh\u00e1ng th\u1ec3.\u00a0S\u1ef1 k\u1ebft h\u1ee3p c\u1ee7a c\u00e1c t\u1ebf b\u00e0o B v\u1edbi c\u00e1c t\u1ebf b\u00e0o u t\u1ee7y t\u1ea1o ra s\u1ef1 k\u1ebft h\u1ee3p c\u1ee7a c\u00e1c t\u1ebf b\u00e0o B b\u1ea5t t\u1eed c\u00f3 th\u1ec3 t\u1ea1o ra c\u00e1c kh\u00e1ng th\u1ec3 c\u1ee5 th\u1ec3.\u00a0T\u1ebf b\u00e0o m\u1edbi n\u00e0y \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 t\u1ebf b\u00e0o lai v\u00e0 n\u00f3 ch\u1ee9a c\u00e1c \u0111\u1eb7c t\u00ednh t\u1ed1t nh\u1ea5t c\u1ee7a c\u1ea3 hai lo\u1ea1i t\u1ebf b\u00e0o.\u00a0D\u00f2ng t\u1ebf b\u00e0o lai b\u00e2y gi\u1edd c\u00f3 th\u1ec3 ph\u00e1t tri\u1ec3n trong m\u00f4i tr\u01b0\u1eddng nu\u00f4i c\u1ea5y v\u00e0 t\u1ea1o ra c\u00e1c kh\u00e1ng th\u1ec3 mong mu\u1ed1n.\u00a0\u0110\u00e2y l\u00e0 nh\u1eefng kh\u00e1ng th\u1ec3 \u0111\u01b0\u1ee3c t\u1ea1o ra \u0111\u1ec3 nh\u1eafm m\u1ee5c ti\u00eau protein trong c\u00e1c ph\u1ea7n m\u00f4 b\u1ec7nh ho\u1eb7c b\u1ec7nh l\u00fd.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"col-12 field__item\">\n<div class=\"text text--simple paragraph paragraph--type--simple-text-element paragraph--view-mode--default\">\n<h2 class=\"text-title\"><span class=\"ez-toc-section\" id=\"Hoa_mo_mien_dich_va_cac_ung_dung_trong_tuong_lai\"><\/span><strong><a href=\"https:\/\/vospan.com\/product-category\/thiet-bi-y-te\/giai-phau-benh\/nhuom-dac-biet-ihc-ish\/\">H\u00f3a m\u00f4 mi\u1ec5n d\u1ecbch<\/a> v\u00e0 c\u00e1c \u1ee9ng d\u1ee5ng trong t\u01b0\u01a1ng lai<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<div>\n<p>C\u00e1c t\u1ebf b\u00e0o ti\u1ebft ra nhi\u1ec1u lo\u1ea1i protein.\u00a0Nh\u1eefng thay \u0111\u1ed5i b\u1ea5t th\u01b0\u1eddng trong t\u1ebf b\u00e0o \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn bi\u1ec3u hi\u1ec7n protein: m\u1ed9t s\u1ed1 protein ng\u1eebng bi\u1ec3u hi\u1ec7n, m\u1ed9t s\u1ed1 kh\u00e1c bi\u1ec3u hi\u1ec7n qu\u00e1 m\u1ee9c v\u00e0 m\u1ed9t s\u1ed1 thay \u0111\u1ed5i th\u00e0nh protein m\u1edbi.\u00a0Vi\u1ec7c ph\u00e2n lo\u1ea1i nh\u1eefng thay \u0111\u1ed5i n\u00e0y d\u1ef1a tr\u00ean khu v\u1ef1c kh\u1edfi ngu\u1ed3n c\u1ee7a ch\u00fang. \u0110\u1ed1i v\u1edbi m\u1ed7i lo\u1ea1i ung th\u01b0 trong m\u1ed9t ph\u00e2n lo\u1ea1i, nghi\u00ean c\u1ee9u \u0111\u00e3 x\u00e1c \u0111\u1ecbnh m\u1ed9t h\u1ed3 s\u01a1 bi\u1ec3u hi\u1ec7n protein \u0111i\u1ec3n h\u00ecnh c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n v\u00e0 hi\u1ec3n th\u1ecb b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng kh\u00e1ng th\u1ec3 &amp; k\u1ef9 thu\u1eadt <a href=\"https:\/\/vospan.com\/product-category\/thiet-bi-y-te\/giai-phau-benh\/nhuom-dac-biet-ihc-ish\/\">IHC<\/a> (H\u00ecnh 4).<\/p>\n<p>Qu\u00e1\u00a0tr\u00ecnh nhu\u1ed9m m\u00e0u \u0111\u01b0\u1ee3c t\u1ea1o ra b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng kh\u00e1ng th\u1ec3 v\u00e0 <a href=\"https:\/\/vospan.com\/product-category\/thiet-bi-y-te\/giai-phau-benh\/nhuom-dac-biet-ihc-ish\/\">IHC<\/a> t\u1ea1o ra d\u1eef li\u1ec7u c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 chuy\u1ec3n sang giai \u0111o\u1ea1n ti\u1ebfp theo c\u1ee7a d\u1ef1 \u00e1n nghi\u00ean c\u1ee9u s\u1eed d\u1ee5ng c\u00e1c c\u00f4ng ngh\u1ec7 c\u1ea3i ti\u1ebfn h\u01a1n nh\u01b0 multiplex, nhu\u1ed9m <a href=\"https:\/\/vospan.com\/product-category\/thiet-bi-y-te\/giai-phau-benh\/nhuom-dac-biet-ihc-ish\/\">IHC<\/a> v\u1edbi nhi\u1ec1u kh\u00e1ng th\u1ec3 tr\u00ean c\u00f9ng m\u1ed9t lam k\u00ednh. B\u1eb1ng c\u00e1ch t\u1ed1i \u0111a h\u00f3a l\u01b0\u1ee3ng d\u1eef li\u1ec7u t\u1eeb m\u1ed9t ph\u1ea7n m\u00f4 duy nh\u1ea5t, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u c\u00f3 th\u1ec3 ph\u00e1t hi\u1ec7n ra c\u00e1c m\u1ed1i t\u01b0\u01a1ng quan d\u1eabn \u0111\u1ebfn ph\u00e1t hi\u1ec7n r\u00f5 h\u01a1n v\u1ec1 qu\u00e1 tr\u00ecnh b\u1ec7nh v\u00e0 m\u00f4i tr\u01b0\u1eddng vi m\u00f4 kh\u1ed1i u.<\/p>\n<p><em>Ngu\u1ed3n: <a href=\"https:\/\/www.leicabiosystems.com\/life-sciences-and-research-solutions\/articles\/an-introduction-to-immunohistochemistry-ihc\/\" target=\"_blank\" rel=\"noopener\">https:\/\/www.leicabiosystems.com\/life-sciences-and-research-solutions\/articles\/an-introduction-to-immunohistochemistry-ihc\/<\/a><\/em><\/p>\n<div class=\"mt-5\">\n<div class=\"col-12 field__item\">\n<div class=\"text text--simple paragraph paragraph--type--simple-text-element paragraph--view-mode--default\">\n<div>\n<div class=\"mt-5\">\n<div class=\"col-12 field__item\">\n<div class=\"text text--simple paragraph paragraph--type--simple-text-element paragraph--view-mode--default\">\n<div class=\"col-12 field__item\">\n<div class=\"text text--simple paragraph paragraph--type--simple-text-element paragraph--view-mode--default\">\n<div>\n<div class=\"col-12 field__item\">\n<div class=\"text text--simple paragraph paragraph--type--simple-text-element paragraph--view-mode--default\">\n<div>\n<div class=\"col-12 field__item\">\n<div class=\"text text--simple paragraph paragraph--type--simple-text-element paragraph--view-mode--default\">\n<div>\n<div class=\"col-lg-3\">\n<div class=\"kp-cta-gray\">\n<div class=\"text-align-center kp-cta--cont\">\n<div class=\"col-12 field__item\">\n<div class=\"media media--simple text--simple paragraph paragraph--type--simple-media-element paragraph--view-mode--default text-align-center\">\n<div class=\"float-md-center no-image-lightbox\">\n<div class=\"media-caption\" data-caption=\" Fig.1: Correctly grossed joint\/tissue\">\n<div class=\"media-image-item-block\">\n<div>\n<div class=\"col-12 field__item\">\n<div class=\"text text--simple paragraph paragraph--type--simple-text-element paragraph--view-mode--default\">\n<div>\n<div>\n<p><strong>Minh Khang l\u00e0 nh\u00e0 ph\u00e2n ph\u1ed1i v\u00e0 nh\u1eadp kh\u1ea9u tr\u1ef1c ti\u1ebfp c\u00e1c thi\u1ebft b\u1ecb\u00a0<a href=\"https:\/\/www.leicabiosystems.com\/en-sg\/\" target=\"_blank\" rel=\"noopener\">Gi\u1ea3i ph\u1eabu b\u1ec7nh<\/a>\u00a0t\u1eeb h\u00e3ng\u00a0<a href=\"https:\/\/www.leicabiosystems.com\/\" target=\"_blank\" rel=\"noopener\">Leica Biosystems<\/a>.<\/strong><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Hi\u1ec7n nay, ho\u00e1 m\u00f4 mi\u1ec5n d\u1ecbch \u0111\u00e3 tr\u1edf th\u00e0nh m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p ph\u1ed5 bi\u1ebfn, l\u00fd t\u01b0\u1edfng cho c\u00e1c nh\u00e0 gi\u1ea3i ph\u1eabu b\u1ec7nh trong vi\u1ec7c chu\u1ea9n \u0111o\u00e1n b\u1ec7nh. IHC l\u00e0 g\u00ec? C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u s\u1eed d\u1ee5ng ph\u01b0\u01a1ng ph\u00e1p nhu\u1ed9m m\u00f4 b\u1ec7nh h\u1ecdc \u0111\u1ec3 kh\u00e1m ph\u00e1 nh\u1eefng ph\u00e1t hi\u1ec7n m\u1edbi trong m\u1ed9t m\u1eabu m\u00f4. \u0110i\u1ec1u n\u00e0y&#8230;<\/p>\n","protected":false},"author":3,"featured_media":9143,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[40],"tags":[],"class_list":["post-9136","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"acf":[],"_links":{"self":[{"href":"https:\/\/vospan.com\/wp-json\/wp\/v2\/posts\/9136"}],"collection":[{"href":"https:\/\/vospan.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vospan.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vospan.com\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/vospan.com\/wp-json\/wp\/v2\/comments?post=9136"}],"version-history":[{"count":11,"href":"https:\/\/vospan.com\/wp-json\/wp\/v2\/posts\/9136\/revisions"}],"predecessor-version":[{"id":11885,"href":"https:\/\/vospan.com\/wp-json\/wp\/v2\/posts\/9136\/revisions\/11885"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vospan.com\/wp-json\/wp\/v2\/media\/9143"}],"wp:attachment":[{"href":"https:\/\/vospan.com\/wp-json\/wp\/v2\/media?parent=9136"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vospan.com\/wp-json\/wp\/v2\/categories?post=9136"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vospan.com\/wp-json\/wp\/v2\/tags?post=9136"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}