Newborn Screening РC̫ng ty TNHH TM DV KT Minh Khang //vospan.com Tue, 12 Apr 2022 08:39:25 +0000 en-US hourly 1 //wordpress.org/?v=6.1.4 //vospan.com/wp-content/uploads/2021/02/favicon-32x32.png Newborn Screening РC̫ng ty TNHH TM DV KT Minh Khang //vospan.com 32 32 Newborn Screening РC̫ng ty TNHH TM DV KT Minh Khang //vospan.com/en/san-pham/hplc-kit-for-pku/ //vospan.com/en/san-pham/hplc-kit-for-pku/#respond Fri, 26 Feb 2021 08:23:04 +0000 //vospan.com/?post_type=product&p=4074
  • Quick and simple sample preparation steps, no need to use SPE for clean up
  • 11.0 minutes analysis time.
  • Quick and simple sample preparation steps-just protein precipitation for plasma
  • Quick and simple sample preparation steps-just
    • ]]>     Phenylketonuria, also called PKU, is a rare inherited disorder that causes an amino acid called
    phenylalanine to build up in the body. PKU is caused by a defect in the gene that helps create the
    enzyme needed to break down phenylalanine.
    Without the enzyme necessary to process phenylalanine, a dangerous buildup can develop when a
    person with PKU eats foods that contain protein or eats aspartame, an artificial sweetener. This can
    eventually lead to serious health problems.
    For the rest of their lives, people with PKU �babies, children and adults �need to follow a diet
    that limits phenylalanine, which is found mostly in foods that contain protein.
    Babies are screened for PKU soon after birth. Recognizing PKU right away can help prevent major
    health problems.
    It can be quantitatively determined by the Jasem PKU HPLC Analysis Kit.

    ]]>     //vospan.com/en/san-pham/hplc-kit-for-pku/feed/ 0     Newborn Screening РC̫ng ty TNHH TM DV KT Minh Khang //vospan.com/en/san-pham/new-born-screening-kit/ //vospan.com/en/san-pham/new-born-screening-kit/#respond Fri, 26 Feb 2021 08:21:26 +0000 //vospan.com/?post_type=product&p=4073
      • Analysis from DBS extraction without derivatization
      • Profile of amino acids&free carnitine/acylcarnitines could be modified/widened for clinical applications
      • Consisting of three scan types-Precursor Ion, Neutral Loss and MRM in the sequence
    Precursor ion scanning: Detection of characteristic mass
    ]]>     Newborn screening is intended to identify inborn error of metabolism thereby making early therapeutic interventions and decreasing likelihood of mortality or lifelong disability. Tandem mass spectrometry (MS/MS) detects abnormal levels of amino acids, free carnitine and acylcarnitines indicating defects of amino acid metabolism such as phenylketonuria(PKU) and maple syrup urine disease (MSUD), defects of organic acid oxidation metabolism and fatty acid oxidation metabolic disorders on account of enzyme deficiency in biochemical pathways.
    Jasem’s newborn screening of amino acids and acylcarnitines extracted from a single of a dried-blood spot (DBS), with stable-isotope-labeled internal standards and without derivatization, can be performed with 3.5 min of instrument time.

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