Jasem – C么ng ty TNHH TM DV KT Minh Khang //vospan.com Wed, 13 Apr 2022 07:36:14 +0000 en-US hourly 1 //wordpress.org/?v=6.1.4 //vospan.com/wp-content/uploads/2021/02/favicon-32x32.png Jasem – C么ng ty TNHH TM DV KT Minh Khang //vospan.com 32 32 Jasem – C么ng ty TNHH TM DV KT Minh Khang //vospan.com/en/san-pham/hvavma5-hiaa-kit/ //vospan.com/en/san-pham/hvavma5-hiaa-kit/#respond Fri, 26 Feb 2021 08:46:52 +0000 //vospan.com/?post_type=product&p=4088 Laboratory measurement of vanillylmandelic acid (VMA), the end product of epinephrine, norepinephrine metabolism, and homovanillic acid (HVA), a terminal metabolite of dopamine, and 5-Hydroxyindolacetic acid (5-HIAA) the end metabolite of serotonin is used to enhance clinical diagnosis and management of catecholamine-secreting neurochromaffin tumors such as neuroblastomas. Neuroblastoma usually emerges in children and accounts for 7鈥?0% of childhood cancer; approximately 90% of these tumors produce catecholamines (CAs). Pheochromocytoma is a rare neuroendocrine tumor arising from the chromaffin cells of the adrenal medulla and characterized by producing excessive amounts of CAs and their metabolites.

]]> //vospan.com/en/san-pham/hvavma5-hiaa-kit/feed/ 0 Jasem – C么ng ty TNHH TM DV KT Minh Khang //vospan.com/en/san-pham/catecholamines-free-metanephrines-and-serotonin/ //vospan.com/en/san-pham/catecholamines-free-metanephrines-and-serotonin/#respond Fri, 26 Feb 2021 08:45:26 +0000 //vospan.com/?post_type=product&p=4086 Jasem聽presents this analysis reliably on LC-MS/MS with free metanephrine, catecholamine and serotonin kit in urine.]]> The major metabolites of catecholamines secreted by the adrenal glands in case of stress are metanephrine, epinephrine, normetanephrine and norepinephrine. These biomarkers are evaluated to determine urinary concentration of them in people with suspected pheochromocytoma. This disease is a very rare tumour and causes hypertension in nonfollowed cases. It is very important to accurately diagnose before surgical intervention and by looking at the catecholamine derivatives, it is possible to diagnose pheochromocytoma.

 

]]> //vospan.com/en/san-pham/catecholamines-free-metanephrines-and-serotonin/feed/ 0 Jasem – C么ng ty TNHH TM DV KT Minh Khang //vospan.com/en/san-pham/serotonin-in-plasma/ //vospan.com/en/san-pham/serotonin-in-plasma/#respond Fri, 26 Feb 2021 08:44:08 +0000 //vospan.com/?post_type=product&p=4085 Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter synthesized from the amino acid tryptophan. Most of total body serotonin is found in the gastrointestinal (GI) tract, where it modulates the functions of the bowel by controlling smooth muscle contraction. It also acts as a cardiovascular vasoconstriction mediator and in the brain as a neurotransmitter.Neuroendocrine neoplasms (NENs), which originate from GI tract enterochromaffin cells, may produce large amounts of serotonin.

 

]]> //vospan.com/en/san-pham/serotonin-in-plasma/feed/ 0 Jasem – C么ng ty TNHH TM DV KT Minh Khang //vospan.com/en/san-pham/metanephrines/ //vospan.com/en/san-pham/metanephrines/#respond Fri, 26 Feb 2021 08:42:34 +0000 //vospan.com/?post_type=product&p=4083 Jasem kit allows simultaneous quantification of free metanephrines in plasma without using SPE throughout 6.5 minutes.]]> Normetanephrine and metanephrine are the O-methylated derivatives of the catecholamine hormones norepinephrine and epinephrine, respectively. Metanephrines are created by means of catecholamine metabolism but also generated excessively in pheochromocytoma tumors of the chromaffin cells, most of which are localized to the adrenal gland. The majority of patients with a pheochromocytoma tumor have plasma normetanephrine and metanephrine concentrations at least 2鈥? times the upper reference limits. The presence of elevated concentrations of the analytes represents as a confirmation tool for the diagnosis of the tumor. In this context, the measurement of free (unconjugated) plasma metanephrines has been proved to be a highly sensitive (With a diagnostic sensitivity of 98% and specificity of 92%) test for the detection of pheochromocytoma.

]]> //vospan.com/en/san-pham/metanephrines/feed/ 0 Jasem – C么ng ty TNHH TM DV KT Minh Khang //vospan.com/en/san-pham/catecholamines/ //vospan.com/en/san-pham/catecholamines/#respond Fri, 26 Feb 2021 08:41:14 +0000 //vospan.com/?post_type=product&p=4081 Plasma catecholamines including epinephrine (E), norepinephrine (NE), and dopamine (DA) are used to evaluate adrenosympathetic function in patients. Quantification of plasma catecholamine concentrations is clinically important for the diagnosis of pheochromocytoma and paraganglioma during dynamic clonidine tests. The low circulating concentrations of catecholamines and analytical interferences require tedious sample preparation and long chromatographic runs to ensure their accurate quantification by HPLC with electrochemical detection.

]]> //vospan.com/en/san-pham/catecholamines/feed/ 0 Jasem – C么ng ty TNHH TM DV KT Minh Khang //vospan.com/en/san-pham/very-long-chain-fatty-acids-vlcfa/ //vospan.com/en/san-pham/very-long-chain-fatty-acids-vlcfa/#respond Fri, 26 Feb 2021 08:37:34 +0000 //vospan.com/?post_type=product&p=4080
  • Very long-chain fatty acids, (VLCFA) pristanic and phytanic acid analysis to aid in diagnosis of peroxisomal biogenesis disorders (Zellweger Syndrome Spectrum), X-linked adrenoleukodystrophy (X- ALD).
  • Detection of multiple target analytes include pristanic and phytanic acids in a single run (14 min).
    • ]]>     Peroxisomes are organelles surrounded by membrane in the form of spheres. Peroxisomes play an important role in beta oxidation of very long chain fatty acids (C22:0, C24:0, C26:0) and alpha oxidation of 3-methyl fatty acids (phytanic acid). The Zellweger syndrome is best known peroxisomal disorders. Zellweger syndrome is a rare disease characterized by decreased or absent peroxisomes in the cells of the liver, kidney and brain. Increased levels of very long chain fatty acids (VLCFA) in blood and decreased plasmalogen levels in erythrocytes are the most important parameters to aid in diagnosis.

    VERY LONG CHAIN FATTY ACIDS, PRISTANIC AND PHYTANIC ACIDS

    The diagnosis of X-ALD may be raised by the above clinical signs or symptoms, including isolated adrenal insufficiency and is commonly achieved by laboratory evaluation of increased concentrations of VLCFA in plasma. Testing typically includes three VLCFA parameters: the level of hexacosanoic acid (C26:0), and the ratio of hexacosanoic acid to tetracosanoic acid (C26:0/ C24:0), and to docosanoic acid (C26:0/C22:0).

    ]]>     //vospan.com/en/san-pham/very-long-chain-fatty-acids-vlcfa/feed/ 0     Jasem – C么ng ty TNHH TM DV KT Minh Khang //vospan.com/en/san-pham/steroid-hormones-kit/ //vospan.com/en/san-pham/steroid-hormones-kit/#respond Fri, 26 Feb 2021 08:35:47 +0000 //vospan.com/?post_type=product&p=4078
  • Using a simple liquid鈥搇iquid-extraction (LLE) protocol for preparation of specimen聽and no derivatization is needed
  • Detection of multiple target analytes in a single run
  • Measurement of multi-class steroids without sacrificing analysis time
  • Ensure accurate quantitation, high sensitivity and selectivity comparing to聽immunoassays
    • ]]>     Steroid hormones are defined as effective biological messengers which take part in crucial body processes even at low concentrations. Thus, dependable and simultaneous analysis of a broad panel of steroid hormones plays vital role for the investigation of the hormone profile, which could be useful in detection endocrine disorders resulting from defects in steroid biosynthesis such as congenital adrenal hyperplasia (CAH). Due to the restrictions and shortcomings of immunoassay techniques for measurement of steroid hormones in body fluids, liquid chromatography tandem mass spectrometry (LC-MS/MS) is increasingly becoming the method for multi-class steroid hormone detection.

    Jasem鈥檚 approach is offering simultaneously quantification of clinically prominent 16 steroid hormones by LC-MS/MS in 16 minutes.

    ]]>     //vospan.com/en/san-pham/steroid-hormones-kit/feed/ 0     Jasem – C么ng ty TNHH TM DV KT Minh Khang //vospan.com/en/san-pham/quantitative-organic-acids-lc-ms-ms-kit/ //vospan.com/en/san-pham/quantitative-organic-acids-lc-ms-ms-kit/#respond Fri, 26 Feb 2021 08:26:27 +0000 //vospan.com/?post_type=product&p=4077
  • Analysis of 54 organic acids without derivatization.
  • Quick and easy sample preparation; just dilution!
  • 12 minutes run for each panel (Total analysis time 24 minutes-Panel 1&2)
  • Successful chromatographic separation of isomers.
    • ]]>     Human urine is a complex biofluid of diverse small polar metabolites such as organic acids. Organic acidurias are inborn errors of metabolism given rise to by defections of inherited enzymes which lead to accumulation excess amounts of normal organic acids in human urine. For this reason qualitative and quantitative analyses of urinary organic acids are prominent diagnostic tools for the interpretation of metabolite profile that reflects inherited metabolic disorders. Conventionally gas chromatography coupled to mass sepectrometry (GC-MS) is used in spite of disadvantages as limititaton to volatile and thermally stable analytes thereby obligating of time consuming derivatization process.

    At this point, 鈥淛asem-Organic Acids鈥?method overcomes abovementioned drawbacks by using liquid chromatography tandem mass spectrometry (LC-MS/MS). Jasem method ensures quantification of 54 organic acids by absence of derivatization simplified sample preperation to diluting. Jasem offers two panels achieving sufficient chromatographic separation for crucial isomers by LC-MS/MS.

    ]]>     //vospan.com/en/san-pham/quantitative-organic-acids-lc-ms-ms-kit/feed/ 0     Jasem – C么ng ty TNHH TM DV KT Minh Khang //vospan.com/en/san-pham/hplc-kit-for-pku/ //vospan.com/en/san-pham/hplc-kit-for-pku/#respond Fri, 26 Feb 2021 08:23:04 +0000 //vospan.com/?post_type=product&p=4074
  • Quick and simple sample preparation steps, no need to use SPE for clean up
  • 11.0 minutes analysis time.
  • Quick and simple sample preparation steps-just protein precipitation for plasma
  • Quick and simple sample preparation steps-just
    • ]]>     Phenylketonuria, also called PKU, is a rare inherited disorder that causes an amino acid called
    phenylalanine to build up in the body. PKU is caused by a defect in the gene that helps create the
    enzyme needed to break down phenylalanine.
    Without the enzyme necessary to process phenylalanine, a dangerous buildup can develop when a
    person with PKU eats foods that contain protein or eats aspartame, an artificial sweetener. This can
    eventually lead to serious health problems.
    For the rest of their lives, people with PKU 鈥?babies, children and adults 鈥?need to follow a diet
    that limits phenylalanine, which is found mostly in foods that contain protein.
    Babies are screened for PKU soon after birth. Recognizing PKU right away can help prevent major
    health problems.
    It can be quantitatively determined by the Jasem PKU HPLC Analysis Kit.

    ]]>     //vospan.com/en/san-pham/hplc-kit-for-pku/feed/ 0     Jasem – C么ng ty TNHH TM DV KT Minh Khang //vospan.com/en/san-pham/new-born-screening-kit/ //vospan.com/en/san-pham/new-born-screening-kit/#respond Fri, 26 Feb 2021 08:21:26 +0000 //vospan.com/?post_type=product&p=4073
      • Analysis from DBS extraction without derivatization
      • Profile of amino acids&free carnitine/acylcarnitines could be modified/widened for clinical applications
      • Consisting of three scan types-Precursor Ion, Neutral Loss and MRM in the sequence
    Precursor ion scanning:聽Detection of characteristic mass
    ]]>     Newborn screening is intended to identify inborn error of metabolism thereby making early therapeutic interventions and decreasing likelihood of mortality or lifelong disability. Tandem mass spectrometry (MS/MS) detects abnormal levels of amino acids, free carnitine and acylcarnitines indicating defects of amino acid metabolism such as phenylketonuria(PKU) and maple syrup urine disease (MSUD), defects of organic acid oxidation metabolism and fatty acid oxidation metabolic disorders on account of enzyme deficiency in biochemical pathways.
    Jasem鈥檚 newborn screening of amino acids and acylcarnitines extracted from a single of a dried-blood spot (DBS), with stable-isotope-labeled internal standards and without derivatization, can be performed with 3.5 min of instrument time.

    ]]>     //vospan.com/en/san-pham/new-born-screening-kit/feed/ 0     Jasem – C么ng ty TNHH TM DV KT Minh Khang //vospan.com/en/san-pham/4066/ //vospan.com/en/san-pham/4066/#respond Fri, 26 Feb 2021 04:40:46 +0000 //vospan.com/?post_type=product&p=4066
  • Quick and simple sample preparation steps
  • No need to use SPE for clean up
  • Dilute and shoot for urine samples
  • Simultaneous analysis of different drug groups-total run time is 12 minutes
  • Method allows to extend the drug list
    • ]]>     //vospan.com/en/san-pham/4066/feed/ 0     Jasem – C么ng ty TNHH TM DV KT Minh Khang //vospan.com/en/san-pham/busulfan-methotrexate-kit/ //vospan.com/en/san-pham/busulfan-methotrexate-kit/#respond Fri, 26 Feb 2021 04:38:42 +0000 //vospan.com/?post_type=product&p=4064
  • Quick and simple sample preparation steps
  • No need SPE cleaning for samples
  • Allows to analyse both drugs in same injection
  • Shorter sample prep and instrument run time
    • ]]>     //vospan.com/en/san-pham/busulfan-methotrexate-kit/feed/ 0